Can You Use Distilled Water in a Nebulizer? What To Use Instead

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Can You Use Distilled Water in a Nebulizer? What To Use Instead
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TL;DR: Do not nebulize distilled water. It is not guaranteed sterile and its very low salt content can irritate your airways. Use sterile 0.9% saline or prescribed medications in unit-dose vials; use 3% to 7% hypertonic saline only if your clinician prescribes it. For cleaning, you may rinse parts with sterile or distilled water after washing, then air-dry completely, but never use these as the treatment liquid. The practical takeaway: only sterile saline or prescribed meds belong in the nebulizer cup.

Can You Use Distilled Water in a Nebulizer? What To Use Instead

No, don't use distilled water as a nebulizer treatment. It isn't guaranteed sterile, especially once opened, and its low salt content can irritate your airways. Distilled water is different from sterile saline; saline is specially prepared and sealed so it’s safe to inhale. Distilled water is not safe to inhale in a nebulizer because it isn’t guaranteed sterile and its lack of salt can irritate your lungs.

Nebulizers are meant for sterile saline or medicines your doctor prescribes.

Why Distilled Water Is a Problem

Distilled water isn’t a safe nebulizer liquid because it isn’t guaranteed sterile and its lack of salt can make your airways react.

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About 1 in 10 people with Legionnaires' disease die (CDC). Avoid nebulizing nonsterile water that can harbor Legionella.

What To Use Instead

In short, the only safe liquids to put in a nebulizer are doctor-prescribed medications or sterile saline solutions.

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Coverage note: Many insurers, including Medicare Part B, may cover nebulizers and some inhaled medications as durable medical equipment when medically necessary. Ask your clinician and plan about required documentation and approved suppliers.

Quick Do/Don’t

Here’s a quick snapshot of what belongs in your nebulizer and what doesn’t.

  • Do use: sterile 0.9% saline; prescribed solutions in unit-dose vials.
  • Don’t use: tap water, boiled or filtered water, bottled water, distilled water, essential oils, or homemade mixtures.
  • If you see boxes labeled "steam inhaler" in the store, remember these are not nebulizers and are not meant for breathing medications.

Use saline or prescribed meds in your nebulizer, and avoid all types of plain water or oils.

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Fast facts:0.9% saline is isotonic and generally well tolerated.Hypertonic saline (3% to 7%) may help mucus clearance but can briefly increase cough; use only if prescribed.Distilled, boiled, or bottled water are not sterile for inhalation.Tap water can harbor microbes; see CDC Emerging Infectious Diseases.

Cleaning Tip

If it matches your device instructions, you can rinse parts with sterile or distilled water after washing to minimize mineral spots, then air-dry completely. Distilled water is fine for rinsing parts after washing but should never be used as the actual treatment liquid. Don’t fill the cup with distilled water for a treatment.

A portable mesh nebulizer like TruNeb™ can make taking saline or prescribed meds simpler at home or on the go. It’s quiet, compact, and designed to be easy to clean between uses.

Infographic titled Nebulizer Liquids: Use vs Avoid with columns for safe and unsafe nebulizer liquids
Two-column medical infographic comparing which liquids to use in a nebulizer versus which to avoid, listing sterile saline and prescribed medications on the left and tap water, non-sterile waters, essential oils, and steam inhalers to avoid on the right.

Safety Notes for Nebulizer Liquids

Always check with your doctor before changing what you put in your nebulizer, and get urgent help if breathing treatments make your symptoms worse.

  • Talk to your doctor before trying a new medication or changing saline strength.
  • If a treatment causes severe cough or wheeze, pause and contact your doctor for guidance.
  • Never nebulize tap water, distilled water, or essential oils.
  • ⚠️ If you or your child has trouble breathing, chest pain, bluish lips or face, or feels like you can’t catch your breath, seek emergency medical care right away (call 911 in the U.S.).

You’ll get better results by using the right solution, cleaning your device regularly, and following your care plan. Talk with your doctor if your symptoms don’t improve or you’re unsure which solution to use.

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CDC Emerging Infectious Diseases notes that household tap water is not sterile and has been linked to serious lung infections when aerosolized; only use sterile saline or prescribed solutions in nebulizers.

Bottom Line

Bottom line: do not nebulize distilled or tap water. Stick with sterile saline or the medications your doctor prescribes.

Medical Disclaimer

Disclaimer: This article is for informational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always talk with your doctor about your symptoms, treatment options, and what to put in your nebulizer.

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