Mucus Thinning Drugs for Cystic Fibrosis: How They Work
💡TL;DR: Hypertonic saline, dornase alfa (Pulmozyme), and inhaled mannitol thin CF mucus so you can clear it. Saline is widely used and relatively low cost, Pulmozyme has strong evidence but higher cost and device requirements, and mannitol is for adults only after a clinic tolerance test. In a 48-week